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SHR Neuro Cancer Cardio Lipid Metab Microb
Dobec-Meić, B; Pikija, S; Cvetko, D; Trkulja, V; Pazanin, L; Kudelić, N; Rotim, K; Pavlicek, I; Kostanjevec, AR.
Intracranial tumors in adult population of the Varazdin County (Croatia) 1996-2004: a population-based retrospective incidence study.
J Neurooncol. 2006; 78(3): 303-10.
Doi: 10.1007/s11060-005-9100-2
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- Pikija Slaven
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- Abstract:
- AIM: To estimate the incidence of intracranial tumors in the adult population of the Varazdin County, Croatia, for the 1996-2004 period. SETTING: Varazdin County General Hospital and four university hospitals in Zagreb, the capital of Croatia. STUDY PERIOD: January 1, 1996 to December 31, 2004. Incident patients: county residents admitted for newly diagnosed intracranial tumors according to the WHO diagnostic criteria. Demographic data were extracted from the 2001 Croatian census. Incidence rates (IRs) per 100,000 person-years (p-y) and annual IRs (per 100,000 persons) were determined and compared as incidence rate ratios (IRRs) with 95% CI. RESULTS: For primary intracranial tumors (PITs), IR was 12.1/100,000 p-y (95% CI: 10.3-14.2), comparable in men and women. The highest incidence was recorded for glioblastoma (IR 4.8, 3.7-6.2) and meningioma (IR 3.1, 2.2-4.2). The incidence of PIT was somewhat greater than that of metastatic tumors (IRR 1.58, 95% CI: 1.22-2.05, P < 0.001). Metastatic tumors were more frequent in men than in women, especially metastatic lung tumors (IRR 6.08, 2.32-20.16, P < 0.001). IRs of all PIT taken together, neuroepithelial tumors cumulatively, nonepithelial tumors cumulatively, glioblastoma and meningioma were higher in the population aged > or = 40 vs. population aged < or = 39 (all IRRs with 95% CI greater than 1, P < 0.05 or < 0.001), comparable in men and women. Women were somewhat older than men at the time of diagnosis of PIT: median difference -6 years (95.1% CI: -10 to -1, P < 0.05). Annual IRs for all these tumor categories showed increasing trends over the study period. CONCLUSION: Overall, there was an increasing trend in the incidence of primary intracranial tumors in the Varazdin County. Data did not allow estimation for most of the specific tumor types.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Age Distribution - administration & dosage
- Aged - administration & dosage
- Brain Neoplasms - classification, epidemiology
- Cohort Studies - administration & dosage
- Confidence Intervals - administration & dosage
- Croatia - epidemiology
- Female - administration & dosage
- Glioblastoma - epidemiology
- Humans - administration & dosage
- Incidence - administration & dosage
- Male - administration & dosage
- Meningioma - epidemiology
- Middle Aged - administration & dosage
- Retrospective Studies - administration & dosage
- Sex Distribution - administration & dosage
- Statistics, Nonparametric - administration & dosage
- Find related publications in this database (Keywords)
- intracranial tumors
- Croatia
- epidemiology