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SHR Neuro Cancer Cardio Lipid Metab Microb
Mutzenbach, SJ; Millesi, K; Roesler, C; Broussalis, E; Pikija, S; Sellner, J; Machegger, L; Griessenauer, CJ; Killer-Oberpfalzer, M.
The Casper Stent System for carotid artery stenosis.
J Neurointerv Surg. 2018; 10(9): 869-873.
Doi: 10.1136/neurintsurg-2017-013583
Web of Science
PubMed
FullText
FullText_MUG
- Co-authors Med Uni Graz
- Pikija Slaven
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- Abstract:
- PURPOSE: To report the results of a retrospective analysis of prospectively collected data evaluating the safety and efficacy of a double layer stent engineered for carotid artery occlusive disease. METHODS: Between January 2014 and February 2017, 138 patients (25.4% women; median age 71 years) underwent Casper stent implantation for carotid artery stenosis. Eligibility criteria included stenosis >70% of vessel diameter (or >50% diameter with ulceration) in symptomatic patients or asymptomatic patients with >80% stenosis at the carotid bifurcation or in the proximal internal carotid artery. For all procedures, a distal embolic protection device was used. The primary endpoint was the rate of 90 day major adverse neurological events, defined as minor stroke, major stroke, or death by independent neurological assessment. RESULTS: Stent deployment was completed successfully in all cases without documented technical failure. There were no adverse neurological events or mortalities within 90 days. One thromboembolic occlusion of a small distal branch of the anterior cerebral artery occurred during the procedure and resolved with systemic recombinant tissue plasminogen activator administration. New ischemic lesions, all clinically silent, were seen in 6.5% of patients on post-procedure cerebral MRI. CONCLUSION: The Casper carotid stent demonstrated safety and efficacy in the treatment of carotid stenosis, with no technical failures and no adverse neurological events seen throughout the 90 day follow-up period. Its double layer structure seems to combine adequate plaque scaffolding with high vessel adaptability.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Aged - administration & dosage
- Aged, 80 and over - administration & dosage
- Carotid Artery, Internal - diagnostic imaging
- Carotid Stenosis - diagnostic imaging, therapy
- Female - administration & dosage
- Follow-Up Studies - administration & dosage
- Humans - administration & dosage
- Male - administration & dosage
- Middle Aged - administration & dosage
- Neurologic Examination - administration & dosage
- Prospective Studies - administration & dosage
- Retrospective Studies - administration & dosage
- Self Expandable Metallic Stents - statistics & numerical data
- Tissue Plasminogen Activator - administration & dosage
- Treatment Outcome - administration & dosage
- Young Adult - administration & dosage
- Find related publications in this database (Keywords)
- carotid artery
- carotid artery stenosis
- carotid artery stent
- nitinol stent
- doublelayer stent
- new stent design