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SHR Neuro Cancer Cardio Lipid Metab Microb
Futyma, P; Sultan, A; Zarębski, Ł; Imnadze, G; Maslova, V; Bordignon, S; Kousta, M; Knecht, S; Pavlović, N; Peichl, P; Lian, E; Kueffer, T; Scherr, D; Pfeffer, M; Moskal, P; Cismaru, G; Antolič, B; Wałek, P; Chen, S; Martinek, M; Kollias, G; Derndorfer, M; Seidl, S; Schmidt, B; Lüker, J; Steven, D; Sommer, P; Jastrzębski, M; Kautzner, J; Reichlin, T; Sticherling, C; Pürerfellner, H; Enriquez, A; Wörmann, J; Chun, JKR.
Bipolar radiofrequency ablation of refractory ventricular arrhythmias: results from a multicentre network.
Europace. 2024; 26(10):
Doi: 10.1093/europace/euae248
[OPEN ACCESS]
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PubMed
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- Co-authors Med Uni Graz
- Scherr Daniel
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- Abstract:
- AIMS: Advanced ablation strategies are needed to treat ventricular tachycardia (VT) and premature ventricular complexes (PVC) refractory to standard unipolar radiofrequency ablation (Uni-RFA). Bipolar radiofrequency catheter ablation (Bi-RFA) has emerged as a treatment option for refractory VT and PVC. Multicentre registry data on the use of Bi-RFA in the setting of refractory VT and PVC are lacking. The aim of this Bi-RFA registry is to determine its real-world safety, feasibility, and efficacy in patients with refractory VT/PVC. METHODS AND RESULTS: Consecutive patients undergoing Bi-RFA at 16 European centres for recurring VT/PVC after at least one standard Uni-RFA were included. Second ablation catheter was used instead of a dispersive patch and was positioned at the opposite site of the ablation target. Between March 2021 and August 2024, 91 patients underwent 94 Bi-RFA procedures (74 males, age 62 ± 13, and prior Uni-RFA range 1-8). Indications were recurrence of PVC (n = 56), VT (n = 20), electrical storm (n = 13), or PVC-triggered ventricular fibrillation (n = 2). Procedural time was 160 ± 73 min, Bi-RFA time 426 ± 286 s, and mean Uni-RFA time 819 ± 697 s. Elimination of clinical VT/PVC was achieved in 67 (74%) patients and suppression of VT/PVC in a further 10 (11%) patients. In the remaining 14 patients (15%), no effect on VT/PVC was observed. Three major complications occurred: coronary artery occlusion, atrioventricular block, and arteriovenous fistula. Follow-up lasted 7 ± 8 months. Nineteen patients (61%) remained VT free. ≥80% PVC burden reduction was achieved in 45 (78%). CONCLUSION: These real-world registry data indicate that Bi-RFA appears safe, is feasible, and is effective in the majority of patients with VT/PVC.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Male - administration & dosage
- Female - administration & dosage
- Middle Aged - administration & dosage
- Tachycardia, Ventricular - surgery, physiopathology
- Ventricular Premature Complexes - surgery, physiopathology, diagnosis
- Catheter Ablation - methods
- Aged - administration & dosage
- Registries - administration & dosage
- Recurrence - administration & dosage
- Treatment Outcome - administration & dosage
- Europe - administration & dosage
- Feasibility Studies - administration & dosage
- Find related publications in this database (Keywords)
- Bipolar ablation
- Ventricular tachycardia
- Premature ventricular complexes
- Advanced ablation strategies