Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Wolfgruber, S; Sedik, S; Klingspor, L; Tortorano, A; Gow, NAR; Lagrou, K; Gangneux, JP; Maertens, J; Meis, JF; Lass-Flörl, C; Arikan-Akdagli, S; Cornely, OA; Hoenigl, M.
Insights from Three Pan-European Multicentre Studies on Invasive Candida Infections and Outlook to ECMM Candida IV.
Mycopathologia. 2024; 189(4):70 Doi: 10.1007/s11046-024-00871-0 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Führende Autor*innen der Med Uni Graz
Hönigl Martin
Sedik Sarah
Wolfgruber Stella
Altmetrics:

Dimensions Citations:

Plum Analytics:

Scite (citation analytics):

Abstract:
Invasive candidiasis and candidemia remain a significant public health concern. The European Confederation of Medical Mycology (ECMM) conducted three pan-European multicentre studies from 1997 to 2022 to investigate various aspects of invasive Candida infections. These studies revealed shifting trends in Candida species distribution, with an increase of non-albicans Candida species as causative pathogens, increasing rates of antifungal resistance, and persistently high mortality rates. Despite advancements in antifungal treatment, the persistently high mortality rate and increasing drug resistance, as well as limited drug access in low-income countries, underscore the need for continued research and development in the treatment of Candida infections. This review aims to summarize the findings of the three completed ECMM Candida studies and emphasize the importance of continued research efforts. Additionally, it introduces the upcoming ECMM Candida IV study, which will focus on assessing candidemia caused by non-albicans Candida species, including Candida auris, investigating antifungal resistance and tolerance, and evaluating novel treatment modalities on a global scale.
Find related publications in this database (using NLM MeSH Indexing)
Humans - administration & dosage
Candidiasis, Invasive - drug therapy, microbiology
Antifungal Agents - therapeutic use, pharmacology
Candida - drug effects, classification, isolation & purification, pathogenicity
Drug Resistance, Fungal - administration & dosage
Europe - epidemiology
Candidemia - drug therapy, microbiology
Multicenter Studies as Topic - administration & dosage

Find related publications in this database (Keywords)
Candida
Candidemia
European Confederation of Medical Mycology (ECMM)
© Med Uni Graz • Impressum