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SHR Neuro Cancer Cardio Lipid Metab Microb
Zeder, K; Douschan, P; Foris, V; Sassmann, T; Maron, BA; Olschewski, H; Kovacs, G.
The prognostic relevance of exercise pulmonary hypertension in cardiac and pulmonary diseases.
Curr Opin Pulm Med. 2024; 30(5):451-458
Doi: 10.1097/MCP.0000000000001096
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Zeder Katarina Eleonora
- Co-authors Med Uni Graz
- Douschan Philipp
- Foris Vasile
- John Teresa
- Kovacs Gabor
- Olschewski Horst
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- Scite (citation analytics):
- Abstract:
- PURPOSE OF REVIEW: In this review, we provide an overview of the prognostic implications of exPH in patients with various common cardiac and pulmonary diseases. RECENT FINDINGS: Exercise pulmonary hypertension (exPH) has been recently re-introduced in the current European Society of Cardiology/European Respiratory Society pulmonary hypertension guidelines. Accordingly, exPH is defined as a mean pulmonary arterial pressure (mPAP)/cardiac output ( CO ) slope greater than 3 mmHg/l/min. Key considerations for this re-introduction included increasing understanding on normal pulmonary hemodynamics during exercise and the broadly available evidence on the association of an abnormal mPAP/ CO slope with poor survival in the general population and in different disease entities. SUMMARY: Exercise (patho-)physiology has opened a new field for clinical research facilitating recognition of cardiovascular and pulmonary vascular diseases in an early stage. Such early recognition with significant prognostic and possibly therapeutic relevance, but being undetectable at rest, makes exercise pulmonary hemodynamics particularly interesting for common diseases, such as valvular heart disease, left heart disease, and chronic pulmonary disease.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Prognosis - administration & dosage
- Hypertension, Pulmonary - physiopathology, diagnosis
- Exercise - physiology
- Hemodynamics - physiology
- Lung Diseases - physiopathology, diagnosis
- Heart Diseases - physiopathology
- Cardiac Output - physiology
- Find related publications in this database (Keywords)
- exercise
- prognosis
- pulmonary hemodynamics
- pulmonary hypertension
- right heart catheterization