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SHR Neuro Cancer Cardio Lipid Metab Microb
Douschan, P; Egenlauf, B; Gall, H; Grünig, E; Hager, A; Heberling, M; Koehler, T; Olschewski, H; Seyfarth, HJ; Yogeswaran, A; Ulrich, S; Kovacs, G.
[New definition and classification of pulmonary hypertension].
Pneumologie. 2023; 77(11): 854-861.
Doi: 10.1055/a-2145-4648
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Douschan Philipp
- Co-authors Med Uni Graz
- Kovacs Gabor
- Olschewski Horst
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- Abstract:
- In the recent ESC/ERS guidelines on the diagnosis and management of pulmonary hypertension (PH) several important changes have been made in respect of the definition and classification of PH.The mPAP cut-off for defining PH was lowered. PH is now defined by an mPAP > 20 mmHg assessed by right heart catheterization. Moreover, the PVR threshold for defining precapillary PH was lowered. Precapillary PH is now defined by a PVR > 2 WU and a pulmonary arterial wedge pressure (PAWP) ≤ 15 mmHg. Furthermore, the increasing evidence for the clinical relevance of pulmonary exercise hemodynamics led to the reintroduction of exercise pulmonary hypertension (EPH) 1. EPH is characterized by a mPAP/CO-slope > 3 mmHg/L/min during exercise testing. In the classification of PH five groups are distinguished: Pulmonary arterial hypertension (group 1), PH associated with left heart disease (group 2), PH associated with lung diseases and/or hypoxia (Group 3), PH associated with pulmonary artery obstructions (group 4) and PH with unclear and/or multi-factorial mechanisms (group 5).In the following guideline-translation we focus on novel aspects regarding the definition and classification of PH and to provide additional background information.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Hypertension, Pulmonary - diagnosis
- Hemodynamics - administration & dosage
- Heart Diseases - administration & dosage
- Cardiac Catheterization - administration & dosage
- Pulmonary Artery - administration & dosage
- Find related publications in this database (Keywords)
- pulmonary hypertension
- definition
- classification