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SHR Neuro Cancer Cardio Lipid Metab Microb

Zimmer, RT; Birnbaumer, P; Sternad, C; Zunner, BEM; Schierbauer, J; Fritsch, M; Fröhlich-Reiterer, E; Hofmann, P; Sourij, H; Aberer, F; Moser, O.
Impact of a 4-week intensive track and field training intervention on glycaemia in adolescents with type 1 diabetes: The ChilDFiT1 study.
Diabetes Obes Metab. 2024; 26(2):631-641 Doi: 10.1111/dom.15352
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Leading authors Med Uni Graz
Moser Othmar
Co-authors Med Uni Graz
Aberer Felix
Fritsch Maria
Fröhlich-Reiterer Elke
Sourij Harald
Sternad Christoph Peter
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Abstract:
AIM: To investigate the safety and efficacy of track and field training compared with intensification of insulin treatment only in adolescents with type 1 diabetes (T1D). MATERIALS AND METHODS: Eighteen adolescents (seven females) with T1D were included (age 15.1 ± 1.1 years, HbA1c 7.3% ± 1.0% [56.3 ± 10.9 mmol/mol]). After a 4-week observational control phase, participants were randomized to either stand-alone intensive glycaemic management (IT; telemedicine or on-site visits, three times/week) or additionally performed track and field exercise (EX; three 60-minute sessions/week) for 4 weeks. Glycaemia was assessed via continuous glucose monitoring during observational control and intervention phases. RESULTS: Time in range (70-180 mg/dL; 3.9-10.0 mmol/L) significantly improved from the observational control phase to the exercise intervention phase in EX (69% ± 13% vs. 72% ± 11%, P = .049), but not in IT (59% ± 22% vs. 62% ± 16%, P = .399). Time below range 1 (54-69 mg/dL; < 3.9 mmol/L) improved in IT (3.1% ± 1.9% vs. 2.0% ± 0.8%, P = .017) and remained stable in EX (2.0% ± 1.7 vs. 1.9% ± 1.1%, P = .999). The EX group's HbA1c ameliorated preintervention to postintervention (mean difference: ΔHbA1c -0.19% ± 0.17%, P = .042), which was not seen within the IT group (ΔHbA1c -0.16% ± 0.37%, P = .40). Glucose standard deviation was reduced significantly in EX (55 ± 11 vs. 51 ± 10 mg/dL [3.1 ± 0.6 vs. 2.8 ± 0.6 mmol/L], P = .011), but not in IT (70 ± 24 vs. 63 ± 18 mg/dL [3.9 ± 1.3 vs. 3.5 ± 1.0 mmol/L], P = .186). CONCLUSION: Track and field training combined with intensive glycaemic management improved glycaemia in adolescents with T1D, which was not observed in the non-exercise group.
Find related publications in this database (using NLM MeSH Indexing)
Female - administration & dosage
Humans - administration & dosage
Adolescent - administration & dosage
Diabetes Mellitus, Type 1 - therapy
Hypoglycemic Agents - therapeutic use
Insulin - therapeutic use
Glycated Hemoglobin - administration & dosage
Blood Glucose Self-Monitoring - administration & dosage
Track and Field - administration & dosage
Blood Glucose - administration & dosage

Find related publications in this database (Keywords)
adolescents
exercise
time in range
type 1 diabetes
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