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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Tandl, V; Haudum, C; Eberhard, K; Hutz, B; Foessl, I; Kolesnik, E; Zirlik, A; von, Lewinski, D; Scherr, D; Verheyen, N; Pieber, T; Obermayer-Pietsch, B.
AMH in Males: Effects of Body Size and Composition on Serum AMH Levels.
J Clin Med. 2023; 12(13):
Doi: 10.3390/jcm12134478
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- Leading authors Med Uni Graz
- Obermayer-Pietsch Barbara
- Tandl Veronika
- Co-authors Med Uni Graz
- Eberhard Katharina
- Fößl Ines
- Haudum Christoph
- Hutz Barbara
- Kolesnik Ewald
- Pieber Thomas
- Scherr Daniel
- Verheyen Nicolas Dominik
- von Lewinski Dirk
- Zirlik Andreas
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- Abstract:
- Serum concentrations of anti-Müllerian hormone (AMH) have been found to decrease with increasing body mass index (BMI) in many studies. It is not yet clear whether this stems from an adverse effect of adiposity on AMH production, or from dilution due to the greater blood volume that accompanies a larger body size. To investigate a possible hemodilution effect, we explored the relationships between serum AMH levels and different parameters of body composition using linear regression models in a cohort of adult males. Body weight, lean mass (LM), and body surface area (BSA) were found to be better predictors of AMH than measures of adiposity, such as BMI or fat mass. Since both LM and BSA correlate with plasma volume better than adipose tissue, we conclude that hemodilution of AMH does occur in adult males and should be considered for normalization in future studies.
- Find related publications in this database (Keywords)
- anti-Mullerian hormone
- hemodilution
- body mass index
- body composition