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SHR Neuro Cancer Cardio Lipid Metab Microb
Kaser, S; Sourij, H; Clodi, M; Schneeweiß, B; Laggner, AN; Luger, A.
[Treatment of acute diabetic metabolic crises in adults (Update 2023) : Hyperglycemic hyperosmolar state and ketoacidotic metabolic disorder].
Wien Klin Wochenschr. 2023; 135(Suppl 1): 237-241.
Doi: 10.1007/s00508-023-02174-8
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- Co-authors Med Uni Graz
- Sourij Harald
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- Abstract:
- Diabetic ketoacidosis (DKA) and the hyperglycemic hyperosmolar state (HHS) represent potentially life-threatening situations in adults. Therefore, rapid comprehensive diagnostic and therapeutic measures with close monitoring of vital and laboratory parameters are required. The treatment of DKA and HHS is essentially the same and replacement of the mostly substantial fluid deficit with several liters of a physiological crystalloid solution is the first and most important step. Serum potassium concentrations need to be carefully monitored to guide its substitution. Regular insulin or rapid acting insulin analogues can be initially administered as an i.v. bolus followed by continuous infusion. Insulin should be switched to subcutaneous injections only after correction of the acidosis and stable glucose concentrations within an acceptable range.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Humans - administration & dosage
- Hyperglycemic Hyperosmolar Nonketotic Coma - diagnosis, therapy
- Diabetic Ketoacidosis - therapy
- Insulin - therapeutic use
- Fluid Therapy - administration & dosage
- Potassium - administration & dosage
- Diabetes Mellitus - drug therapy
- Find related publications in this database (Keywords)
- Diabetic ketoacidosis
- Hyperglycemic hyperosmolar state
- Serum osmolality
- Anion gap
- Pseudohyponatremia