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SHR Neuro Cancer Cardio Lipid Metab Microb
Previato, M; Osto, E; Kerkhof, PLM; Parry, G; Tona, F.
Heart Transplantation Survival and Sex-Related Differences.
Adv Exp Med Biol. 2018; 1065:379-388
Doi: 10.1007/978-3-319-77932-4_24
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Osto Elena
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- Abstract:
- Orthotopic heart transplantation (OHT) is the "gold standard" treatment for patients with end-stage heart failure, with approximately 5000 transplants performed each year worldwide. Heart transplantation survival rates have progressively improved at all time points, despite an increase in donor and recipient age and comorbidity and greater recipient urgency; according to the registry of the International Society of Heart and Lung Transplantation (ISHLT), the median survival of patients posttransplantation is currently 12.2 years.Long-term survival is sub-optimal, and outcomes after OHT remain constrained by the development of acute rejection and cardiac allograft vasculopathy (CAV). Moreover, donor organs are in short supply, making optimal organ utilization an ongoing priority. For these reasons, substantial interest continues to exist in identifying factors portending increased survival and improved organ utilization.
- Find related publications in this database (using NLM MeSH Indexing)
- Female - administration & dosage
- Graft Rejection - etiology
- Graft Survival - administration & dosage
- Health Status Disparities - administration & dosage
- Healthcare Disparities - administration & dosage
- Heart Failure - diagnosis, mortality, physiopathology, surgery
- Heart Transplantation - adverse effects, mortality
- Humans - administration & dosage
- Male - administration & dosage
- Recovery of Function - administration & dosage
- Risk Factors - administration & dosage
- Sex Factors - administration & dosage
- Time Factors - administration & dosage
- Treatment Outcome - administration & dosage
- Find related publications in this database (Keywords)
- Cardiac transplantation
- Allograft vasculopathy
- Sex mismatch
- Donor organ
- Microvasculopathy
- Premenopausal female donor
- Posttransplant mortality
- Immunological difference
- Transfusion history
- United Network for Organ Sharing
- Review