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SHR Neuro Cancer Cardio Lipid Metab Microb
Posch-Pertl, L; List, W; Michelitsch, M; Pinter-Hausberger, S; Posch, F; Innauer, F; Renner, W; Weger, M.
Role of the ABO Blood Groups as a Risk Factor for Retinal Vein Occlusion.
Ophthalmic Res. 2023; 66(1):164-169
Doi: 10.1159/000526874
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Posch-Pertl Laura
- Co-authors Med Uni Graz
- Innauer Felix
- List Wolfgang Michael
- Michelitsch Monja
- Pinter-Hausberger Silke
- Posch Florian
- Renner Wilfried
- Weger Martin
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- Abstract:
- INTRODUCTION: A recent study suggested that non-O blood groups had an increased risk for the presence of retinal vein occlusion (RVO). In this study, we investigated (i) an association between blood group and the presence of RVO and (ii) whether this association correlated to other RVO risk factors. METHODS: We included 485 RVO patients and 295 control subjects who were recruited in this case-control study. We determined ABO genotypes rs8176719 as a marker for the O allele and rs8176746 for the B allele by polymerase chain reaction. RESULTS: We did not find an association between ABO blood group and the presence of RVO. In detail, the proportion of ABO blood groups was similar among RVO patients and control subjects (p = 0.527). In a logistic regression, non-O blood group was associated with 1.06-fold higher odds of being a RVO patient (95% CI: 0.78-1.45, p = 0.693), and this lack of association prevailed upon multivariable adjustment for age, gender, history of stroke and venous thromboembolism, and co-medication with lipid-lowering agents. DISCUSSION: Although non-O blood groups are a known risk factor for thrombotic and cardiovascular disease, they do not seem to be a major risk factor for the development of RVO.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Retinal Vein Occlusion - diagnosis, genetics, complications
- ABO Blood-Group System - genetics
- Case-Control Studies - administration & dosage
- Risk Factors - administration & dosage
- Genotype - administration & dosage