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SHR Neuro Cancer Cardio Lipid Metab Microb

Ivanjko, F; Konstantiniuk, P; Muehlsteiner, J; Cohnert, T.
Effect of distance to the base of skull and tumor size characteristics on cranial nerve injuries in carotid body tumor resections.
J Vasc Surg. 2023; 77(2):523-528 Doi: 10.1016/j.jvs.2022.09.001
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Co-authors Med Uni Graz
Cohnert Tina Ulrike
Konstantiniuk Peter
Mühlsteiner Johanna
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Abstract:
OBJECTIVE: In the present study, we aimed to confirm the findings reported by Kim et al. They stated that the tumor's distance to the base of the skull was predictive of injury to the cranial nerves and their branches during carotid body tumor resection in an Austrian cohort. METHODS: In the present retrospective observational trial, we included all consecutive patients who had been discharged from our tertiary care teaching hospital with the diagnosis of a carotid body tumor (CBT) between January 2004 and December 2019. Tumor-specific parameters were measured from the preoperative contrast-enhanced computed tomography or magnetic resonance imaging studies. Patient-specific data were obtained from the patients' medical records. The effect of these parameters on the occurrence of cranial nerve injuries was calculated using univariate logistic regression analysis. Parameters significant on univariate analysis were included in a multivariate model. RESULTS: A total of 48 CBTs had been resected in 43 patients (29 women [67.4%] and 14 men [32.6%]), with a mean age of 55.6 years (95% confidence interval, 51.8-58.5). The mean distance to the base of the skull was 43.2 mm (95% confidence interval, 39.9-46.5). A total of 18 injuries to the cranial nerves and their branches in 10 CBTs were detected. The tumor-specific parameters that were significant on univariate analysis were the distance to the base of the skull (P = .009), craniocaudal tumor diameter (P = .027), and tumor volume (P = .036). Stepwise multivariate logistic regression analysis revealed that the distance to the base of the skull was the only parameter that remained statistically significant. CONCLUSIONS: We found that the distance to the base of the skull is a highly predictive parameter for injuries to the cranial nerves and their branches during CBT resection and should be included in the surgical risk assessment and patient information.
Find related publications in this database (using NLM MeSH Indexing)
Male - administration & dosage
Humans - administration & dosage
Female - administration & dosage
Middle Aged - administration & dosage
Retrospective Studies - administration & dosage
Carotid Body Tumor - diagnostic imaging, surgery
Treatment Outcome - administration & dosage
Cranial Nerve Injuries - etiology
Skull Base - diagnostic imaging, surgery, pathology

Find related publications in this database (Keywords)
Carotid body tumor resection
CBT resection
Cranial nerve injury
Distance to the base of the skull
DTBOS
Paraganglioma
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