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Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Hoenigl, M; Seidel, D; Sprute, R; Cunha, C; Oliverio, M; Goldman, GH; Ibrahim, AS; Carvalho, A.
COVID-19-associated fungal infections.
Nat Microbiol. 2022; 7(8):1127-1140
Doi: 10.1038/s41564-022-01172-2
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- Führende Autor*innen der Med Uni Graz
- Hönigl Martin
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- Abstract:
- Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an important complication in a substantial number of critically ill, hospitalized patients with COVID-19. Three groups of fungal pathogens cause co-infections in COVID-19: Aspergillus, Mucorales and Candida species, including Candida auris. Here we review the incidence of COVID-19-associated invasive fungal infections caused by these fungi in low-, middle- and high-income countries. By evaluating the epidemiology, clinical risk factors, predisposing features of the host environment and immunological mechanisms that underlie the pathogenesis of these co-infections, we set the scene for future research and development of clinical guidance.