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SHR Neuro Cancer Cardio Lipid Metab Microb

Eckstein, ML; Moser, O; Rössler, A; Moertl, MG; Jantscher, A; Papousek, I; Wagner, J; Schmid-Zalaudek, K; Sourij, H; Treiber, G; Lackner, HK.
Differences in Hemodynamic, Hormonal and Heart Rate Variability Parameters in Complication-Free Pregnancies Compared to Individuals with Gestational Diabetes Mellitus and Preeclampsia: An Observational Retrospective Analysis.
Life (Basel). 2021; 11(7): Doi: 10.3390/life11070626 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Leading authors Med Uni Graz
Eckstein Max Lennart
Moser Othmar
Co-authors Med Uni Graz
Jantscher Andreas
Lackner Helmut Karl
Mörtl Manfred Georg
Rössler Andreas
Schmid-Zalaudek Karin
Sourij Harald
Treiber Gerlies
Wagner Johann
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Abstract:
To investigate differences in hemodynamic, hormonal and heart rate variability parameters in women following complication-free pregnancies (healthy), preeclampsia and gestational diabetes mellitus (GDM) after giving childbirth. Data of 60 women (healthy: n = 29, age 32.7 ± 4.5 years, BMI 24.2 ± 4.3 kg/m2; preeclampsia: n = 16, age 35.3 ± 4.4 years, 28.5 ± 6.4 kg/m2; GDM, n = 15, age 32.3 ± 6.0 years, BMI 26.4 ± 6.2 kg/m2) were included. Two visits were conducted 16 and 48 weeks after giving childbirth. Hair samples were taken for analysis of cortisol and testosterone. ECG and blood pressure were recorded at each visit. Data were analyzed via RM-ANOVA and post-hoc testing (p ≤ 0.05). Heart rate increased from visit 1 to visit 2, whereas SDNN decreased (both p = 0.03). RMSSD showed an increased trend for groups (p = 0.06). Testosterone in the GDM group was significantly higher compared to the other groups (p = 0.002). Cortisol levels were significantly higher following post-hoc testing GDM was different compared to healthy individuals (p = 0.02). Hemodynamic changes from week 16 to week 48 did not differ between groups (p > 0.05). No differences between individuals with preeclampsia and healthy individuals were found for all hemodynamic parameters (p > 0.05). The study showed higher levels of chronic stress indicators in GDM measured via heart rate variability and cortisol compared to women with a history of preeclampsia and healthy women.

Find related publications in this database (Keywords)
gestational diabetes
heart rate variability
autonomic regulation
preeclampsia
testosterone
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