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Jud, P; Kessler, HH; Brodmann, M.
Case Report: Changes of Vascular Reactivity and Arterial Stiffness in a Patient With Covid-19 Infection.
Front Cardiovasc Med. 2021; 8: 671669-671669. Doi: 10.3389/fcvm.2021.671669 (- Case Report) [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Leading authors Med Uni Graz
Jud Philipp
Co-authors Med Uni Graz
Brodmann Marianne
Kessler Harald
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Abstract:
Covid-19 infection may be associated with a higher incidence developing cardiovascular complications, however, the underlying mechanisms contributing to cardiovascular complications are largely unknown, while endothelial cell damage may be present. We want to report a 24-year-old woman with Covid-19 infection who had undergone measurements of vascular reactivity and arterial stiffness, including flow-mediated dilation (FMD), nitroglycerin-mediated dilation (NMD), aortic pulse wave velocity (PWV), augmentation index and carotid intima-media-thickness (cIMT) at the time when Covid-19 was diagnosed. Reduced FMD of 0.0% and NMD of 15.5% were observed, while PWV (5.9 m/s), Aix (27%) and cIMT with 0.4 mm of both common carotid arteries were unremarkable. Repeated measurements of FMD, NMD, PWV, Aix, and cIMT 6 weeks after Covid-19 infection revealed persistently reduced FMD (0.0%), while NMD (17.24%), PWV (5.6 m/s) and augmentation index (13%) ameliorated. This case suggests potential impact of Covid-19 infection on endothelial function, also in young Covid-19 patients without any co-morbidity. Copyright © 2021 Jud, Kessler and Brodmann.

Find related publications in this database (Keywords)
Covid-19
endothelial dysfunction
vascular reactivity
arterial stiffness
vasculopathy
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