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Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J.
Characterization of dermal fibroblast-derived iPSCs from a patient with low grade steatosis.
Stem Cell Res. 2016; 17(3):547-549
Doi: 10.1016/j.scr.2016.10.004
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- Co-Autor*innen der Med Uni Graz
- Zatloukal Kurt
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- Abstract:
- Primary fibroblasts from a low grade steatosis patient were reprogrammed by transduction of a combination of two episomal-based plasmids OCT4,SOX2, c-MYC and KLF4. iPSCs were characterized by immunocytochemistry, embryonic body-formation, DNA-fingerprint karyotype analysis and comparative transcriptome analyses with the human embryonic stem cell line H1 revealed a Pearsons correlation of 0.9251. Copyright © 2016 Michael Boutros, German Cancer Research Center, Heidelberg, Germany. Published by Elsevier B.V. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Cell Differentiation -
- Cell Line -
- Cellular Reprogramming -
- Dermis - cytology
- Embryoid Bodies - cytology
- Embryoid Bodies - metabolism
- Fatty Liver - genetics
- Fatty Liver - pathology
- Female -
- Fibroblasts - cytology
- Humans -
- Induced Pluripotent Stem Cells - cytology
- Induced Pluripotent Stem Cells - metabolism
- Karyotype -
- Microscopy, Fluorescence -
- Sequence Analysis, DNA -
- Transcription Factors - genetics
- Transcription Factors - metabolism