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Wadsack, C; Desoye, G; Hiden, U.
The feto-placental endothelium in pregnancy pathologies.
Wien Med Wochenschr. 2012; 162(9-10):220-224 Doi: 10.1007/s10354-012-0075-2
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Führende Autor*innen der Med Uni Graz
Wadsack Christian
Co-Autor*innen der Med Uni Graz
Desoye Gernot
Hiden Ursula
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Abstract:
This review aims to provide a comprehensive summary of the aspects of endothelial and vascular dysfunction in the feto-placental vasculature occurring in pregnancy pathologies. This endothelium is continuous with the fetal circulation. Its function and potential dysfunction in pathologies will have a profound impact on fetal development. Gestational diabetes mellitus represents one of these pathologies, in which its associated metabolic derangements will alter feto-placental endothelial functions. These, in turn, may result in functional changes of the placenta, which may entail impaired fetal development. By contrast, changes in the feto-placental vasculature observed in cases of fetal growth restriction and preeclampsia may be causative (fetal growth restriction) or secondary (preeclampsia) for the pathology.
Find related publications in this database (using NLM MeSH Indexing)
Diabetes, Gestational - physiopathology
Endothelium, Vascular - physiopathology
Female -
Fetal Growth Retardation - physiopathology
Humans -
Infant, Newborn -
Maternal-Fetal Exchange - physiology
Placenta - blood supply
Pre-Eclampsia - physiopathology
Pregnancy -
Pregnancy Complications - physiopathology
Vascular Endothelial Growth Factor Receptor-1 - physiology
Vascular Resistance - physiology

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