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SHR Neuro Krebs Kardio Lipid Stoffw Microb
Hofmann, NA; Reinisch, A; Strunk, D.
Endothelial colony-forming progenitor cell isolation and expansion.
Methods Mol Biol. 2012; 879(4):381-387
Doi: 10.1007/978-1-61779-815-3_23
PubMed
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- Führende Autor*innen der Med Uni Graz
- Hofmann Nicole
- Co-Autor*innen der Med Uni Graz
- Reinisch Andreas
- Strunk Dirk
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- Abstract:
- Vessel wall-derived somatic endothelial colony-forming progenitor cells (ECFCs) are key players in vascular homeostasis and regeneration. Due to their robust proliferative potential and profound vessel-forming capacity, ECFCs are considered to represent an attractive tool for vascular regenerative medicine and a promising target for antiangiogenic tumor therapy. Here, we describe an easily applicable method for isolating ECFCs directly from unmanipulated adult human blood and an animal protein-free large-scale expansion system to generate more than 100 million functional ECFCs.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Cell Proliferation -
- Cell Separation -
- Endothelial Cells - cytology
- Humans -
- Stem Cells - cytology