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Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lackner, C; Thorell, A; Trauner, M.
Ursodeoxycholic acid for treatment of fatty liver disease and dyslipidemia in morbidly obese patients.
Dig Dis. 2011; 29(1):117-118
Doi: 10.1159/000324146
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Fickert Peter
- Lackner Karoline
- Trauner Michael
- Wagner Martin
- Zollner Gernot
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- Abstract:
- Bile acids have recently been identified as major integrators of hepatic fatty acid and triglyceride metabolism. We explored potential mechanism(s) of action of ursodeoxycholic acid (20 mg/kg/day in 3 weeks) in 40 morbidly obese patients (mean BMI >40 kg/m(2)) with suggested fatty liver disease awaiting bariatric surgery. At follow-up half a year after surgery, patients had decreased their BMI by approximately 10 kg/m(2), which resulted in significant improvements of liver function tests, insulin sensitivity and glucose tolerance. Copyright © 2011 S. Karger AG, Basel.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Dyslipidemias - complications Dyslipidemias - drug therapy
- Fatty Liver - complications Fatty Liver - drug therapy
- Female -
- Glucose Tolerance Test -
- Humans -
- Insulin Resistance -
- Male -
- Obesity, Morbid - complications
- Ursodeoxycholic Acid - therapeutic use
- Find related publications in this database (Keywords)
- Insulin resistance
- Glucose tolerance
- Bariatric surgery