Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Ferré, S; Baler, R; Bouvier, M; Caron, MG; Devi, LA; Durroux, T; Fuxe, K; George, SR; Javitch, JA; Lohse, MJ; Mackie, K; Milligan, G; Pfleger, KD; Pin, JP; Volkow, ND; Waldhoer, M; Woods, AS; Franco, R.
Building a new conceptual framework for receptor heteromers.
Nat Chem Biol. 2009; 5(3): 131-134.
Doi: 10.1038/nchembio0309-131
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- Co-Autor*innen der Med Uni Graz
- Waldhoer Maria
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- Abstract:
- Receptor heteromers constitute a new area of research that is reshaping our thinking about biochemistry, cell biology, pharmacology and drug discovery. In this commentary, we recommend clear definitions that should facilitate both information exchange and research on this growing class of transmembrane signal transduction units and their complex properties. We also consider research questions underlying the proposed nomenclature, with recommendations for receptor heteromer identification in native tissues and their use as targets for drug development.
- Find related publications in this database (using NLM MeSH Indexing)
- Drug Design -
- Receptors, Cell Surface - drug effects
- Signal Transduction -