Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Pikija, S; Magdic, J; Killer-Oberpfalzer, M; Florea, C; Hauer, L; Novak, HF; McCoy, MR; Sellner, J.
Proximal flow to middle cerebral artery is associated with higher thrombus density in terminal internal carotid artery occlusion.
Ann Clin Transl Neurol. 2017; 4(7): 517-521.
Doi: 10.1002/acn3.429
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- Führende Autor*innen der Med Uni Graz
- Pikija Slaven
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- Abstract:
- Proximal collaterals may determine the composition of occluding thrombi in acute ischemic stroke (AIS) in addition to source, hematocrit, time, and medication. Here, we performed a retrospective study of 39 consecutive patients with radiological evidence of I-, L-, and T-type terminal internal carotid artery occlusion. Middle cerebral artery (MCA) thrombus density was assessed on noncontrast enhanced CT and proximal collaterals on CT angiography. In patients with presence of proximal collaterals to the MCA we detected more hyperdense clots (P = 0.003) and a higher frequency of leptomeningeal collaterals (P = 0.008). We expand the spectrum of factors that potentially determine clot perviousness and evolution of ischemic stroke.