Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Sousa, PA; Tonko, J; Dilling-Boer, D; Barra, S; Eberl, AS; Pezo, B; Cortez-Dias, N; Khoueiry, Z; Medeiros, P; Rodríguez-Mañero, M; Lebreiro, A; Pereira, M; Puga, L; Scherr, D; António, N; Ferreira, A; Saleiro, C; Lagrange, P; Adão, L; de, Sousa, J; Elvas, L; Oliveira, M; Gonçalves, L; Silberbauer, J.
Real-world assessment of multipolar and point-by-point mapping for premature ventricular contraction ablation.
Europace. 2024; 26(6):
Doi: 10.1093/europace/euae148
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PubMed
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- Co-Autor*innen der Med Uni Graz
- Eberl Anna-Sophie
- Scherr Daniel
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- Abstract:
- AIMS: We aimed to assess the acute and midterm efficacy of premature ventricular contraction (PVC) ablation guided by multielectrode and point-by-point (PbP) mapping. METHODS AND RESULTS: This is a retrospective, international multicentre study of consecutive patients referred for PVC ablation in 10 hospital centres from January 2017 to December 2021. Based on the mapping approach, two cohorts were identified: the 'Multipolar group', where a dedicated high-density mapping catheter was employed, and the 'PbP group', where mapping was performed with the ablation catheter. Procedural endpoints, safety, and acute (procedural) and midterm efficacies were assessed. Of the 698 patients included in this study, 592 received activation mapping [46% males, median age of 55 (41-65) years]-248 patients in the Multipolar group and 344 patients in the PbP group. A higher number of activation points [432 (217-843) vs. 95 (42-185), P < 0.001], reduced mapping time (40 ± 38 vs. 61 ± 50 min, P < 0.001), and shorter procedure time (124 ± 60 vs. 143 ± 63 min, P < 0.001) were reported in the Multipolar group. Both groups had high acute success rates (84.7% with Multipolar mapping vs. 81.3% with PbP mapping, P = 0.63), as well as midterm efficacy (83.4% vs. 77.4%, P = 0.08), with no significant differences in the risk of adverse events (6.0% vs. 3.5%, P = 0.24). However, for left-sided PVC ablation specifically, there was a higher midterm efficacy in the Multipolar group (80.7% vs. 69.5%, P = 0.04), with multipolar mapping being an independent predictor of success [adjusted OR = 2.231 (95% CI, 1.476-5.108), P = 0.02]. CONCLUSION: The acute and midterm efficacies of PVC ablation are high with both multipolar and PbP mapping, although the former allows for quicker procedures and may potentially improve the outcomes of left-sided PVC ablation.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Ventricular Premature Complexes - surgery, physiopathology, diagnosis
- Male - administration & dosage
- Middle Aged - administration & dosage
- Female - administration & dosage
- Catheter Ablation - methods
- Retrospective Studies - administration & dosage
- Aged - administration & dosage
- Adult - administration & dosage
- Treatment Outcome - administration & dosage
- Electrophysiologic Techniques, Cardiac - administration & dosage
- Find related publications in this database (Keywords)
- Multielectrode mapping catheter
- Point-by-point mapping
- Premature ventricular contraction
- Left-sided premature ventricular contraction
- Catheter ablation