Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Jomard, A; Osto, E.
[Metabolism and Function of High-Density Lipoproteins (HDL)].
Praxis (Bern 1994). 2019; 108(7): 477-486.
Doi: 10.1024/1661-8157/a003241
PubMed
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- Führende Autor*innen der Med Uni Graz
- Osto Elena
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- Abstract:
- Metabolism and Function of High-Density Lipoproteins (HDL) Abstract. HDL has long been considered as 'good cholesterol', beneficial to the whole body and in particular to cardio-vascular health. However, HDL is a complex particle that undergoes dynamic remodeling through interactions with various enzymes and tissue types throughout its life cycle. In this review, we explore the novel understanding of HDL as a multifaceted class of lipoprotein, with multiple subclasses of different size, molecular composition, receptor interactions, and functionality, in health and disease. Further, we report on emergent HDL based therapeutics tested in small and larger scale clinical trials and their mixed successes.
- Find related publications in this database (using NLM MeSH Indexing)
- Cholesterol - administration & dosage
- Humans - administration & dosage
- Lipoproteins - administration & dosage
- Lipoproteins, HDL - physiology
- Metabolism - physiology