Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Egger, M; Gornicec, M; Wölfler, A; Lembeck, AL; Tinchon, C; Maderdonner, M; Prattes, J.
Incidence of invasive fungal infections in patients with hematological malignancies receiving ibrutinib therapy in south-east Austria.
Med Mycol. 2022; 60(9):
Doi: 10.1093/mmy/myac061
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Egger Matthias Florian
- Prattes Jürgen
- Co-Autor*innen der Med Uni Graz
- Wölfler Albert
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- Abstract:
- Since the broad implementation of ibrutinib therapy, an increasing number of studies have been reported on invasive fungal infections (IFI) associated with ibrutinib administration. We conducted a retrospective cohort study in three hospitals in south-east Austria in order to assess the local epidemiology of ibrutinib associated IFIs. A total of 113 patients with underlying hematological malignancy were included in the study. During the study period, a single IFI episode was observed, which corresponds to an IFI incidence of 2.3 cases per 100 person years (95% CI: 0.12-11.47). IFIs during ibrutinib therapy seem to be a rare event in case of absent additional risk factors for IFIs.
- Find related publications in this database (using NLM MeSH Indexing)
- Adenine - analogs & derivatives
- Animals - administration & dosage
- Antifungal Agents - therapeutic use
- Austria - epidemiology
- Hematologic Neoplasms - complications, drug therapy, veterinary
- Humans - administration & dosage
- Incidence - administration & dosage
- Invasive Fungal Infections - complications, drug therapy, epidemiology, veterinary
- Piperidines - administration & dosage
- Retrospective Studies - administration & dosage
- Find related publications in this database (Keywords)
- small molecule kinase inhibitor
- ibrutinib
- hematologic malignancy
- invasive fungal infection