Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Schmid, J; Nagy, E; Kaufmann-Bühler, AK; Steiner, J; Janisch, M; Janek, E; Reiter, C; Eibisberger, M; Softic, N; Guss, H; Fuchsjäger, M; Adelsmayr, G.
Diagnosing Pulmonary Embolism With Computed Tomography Pulmonary Angiography: Diagnostic Accuracy of a Reduced Scan Range.
J Thorac Imaging. 2022; 37(5):323-330
Doi: 10.1097/RTI.0000000000000664
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- Führende Autor*innen der Med Uni Graz
- Schmid Johannes
- Co-Autor*innen der Med Uni Graz
- Adelsmayr Gabriel
- Eibisberger Martin
- Fuchsjäger Michael
- Janek Elmar
- Janisch Michael August Johann
- Kaufmann-Bühler Ann-Katrin
- Nagy Eszter
- Reiter Clemens
- Softic Nina
- Steiner Jakob
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- Abstract:
- PURPOSE: Computed tomography pulmonary angiography (CT-PA) is frequently used in the diagnostic workup of pulmonary embolism (PE), even in highly radiosensitive patient populations. This study aims to assess CT-PA with reduced z -axis coverage (compared with a standard scan range covering the entire lung) for its sensitivity for detecting PE and its potential to reduce the radiation dose. MATERIALS AND METHODS: We retrospectively analyzed 602 consecutive CT-PA scans with definite or possible PE reported. A reduced scan range was defined based on the topogram, where the cranial slice was set at the top of the aortic arch and the caudal slice at the top of the lower hemidiaphragm. Locations of emboli in relation to the reduced scan range were recorded. RESULTS: We included 513 CT-PA scans with definite acute PE in statistical analysis. Patients' median age was 66 (52 to 77) years, 46% were female. Median dose length product was 270.8 (111.3 to 503.9) mGy*cm. Comparing the original and reduced scan ranges, the mean scan length was significantly reduced by 48.0±8.6% (26.8±3.0 vs. 13.9±2.6 cm, P <0.001). Single emboli outside the reduced range in addition to emboli within were found in 15 scans (2.9%), while only 1 scan (0.2%) had an embolus outside the reduced range and none within it. The resulting sensitivity of CT-PA with reduced scan range was 99.81% (95% confidence interval: 98.74%-99.99%) for detecting any PE. CONCLUSION: A reduced scan length in CT-PA, as defined above, would substantially decrease radiation dose while maintaining diagnostic accuracy for detecting PE.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged - administration & dosage
- Angiography - methods
- Computed Tomography Angiography - administration & dosage
- Female - administration & dosage
- Humans - administration & dosage
- Lung - administration & dosage
- Male - administration & dosage
- Pulmonary Embolism - diagnostic imaging
- Radiation Dosage - administration & dosage
- Retrospective Studies - administration & dosage
- Tomography, X-Ray Computed - methods
- Find related publications in this database (Keywords)
- pulmonary embolism
- computed tomography
- pulmonary angiography
- radiation dose
- sensitivity