Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J.
Characterization of dermal fibroblast-derived iPSCs from a patient with high grade steatosis.
Stem Cell Res. 2016; 17(3):568-571
Doi: 10.1016/j.scr.2016.10.007
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- Co-authors Med Uni Graz
- Zatloukal Kurt
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- Abstract:
- Primary fibroblasts from a high grade steatosis patient were reprogrammed by transduction of retroviruses OCT4, SOX2, c-MYC and KLF4. IPSCs were characterized by immunocytochemistry, embryoid body-formation, DNA-fingerprint, karyotype analysis and comparative transcriptome analyses with the human embryonic stem cell line H1 revealed a Pearsons correlation coefficient of 0.9287. Resource table. Copyright © 2016 Michael Boutros, German Cancer Research Center, Heidelberg, Germany. Published by Elsevier B.V. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Cell Differentiation -
- Cell Line -
- Cellular Reprogramming -
- DNA Fingerprinting -
- Dermis - cytology
- Embryoid Bodies - cytology
- Embryoid Bodies - metabolism
- Fatty Liver - metabolism
- Fatty Liver - pathology
- Fibroblasts - cytology
- Genetic Vectors - genetics
- Genetic Vectors - metabolism
- Humans -
- Induced Pluripotent Stem Cells - cytology
- Induced Pluripotent Stem Cells - metabolism
- Karyotype -
- Male -
- Microscopy, Fluorescence -
- Retroviridae - genetics
- Severity of Illness Index -
- Transcription Factors - genetics
- Transcription Factors - metabolism