Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Szolar, DH; Kammerhuber, FH.
Adrenal adenomas and nonadenomas: assessment of washout at delayed contrast-enhanced CT.
Radiology. 1998; 207(2):369-375
Doi: 10.1148/radiology.207.2.9577483
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- Abstract:
- PURPOSE: To measure the changes in wash-in and washout of contrast material on contrast material-enhanced computed tomographic (CT) scans in patients with adrenal adenomas and nonadenomas. MATERIALS AND METHODS: One hundred twenty-two patients with 135 adrenal masses (74 adenomas, 61 nonadenomas) underwent helical CT. Unenhanced CT was followed by enhanced CT at 30, 60, and 90 seconds and 3, 10, and 30 minutes. RESULTS: The adenomas enhanced significantly more than the nonadenomas at 60 seconds (P < .001), but the percentage enhancement of the adenomas was significantly greater than that of the nonadenomas at 30, 60, and 90 seconds (P < .001). At 3, 10, and 30 minutes, the absolute percentage loss of enhancement and the relative percentage loss of enhancement were significantly greater for the adenomas than for the nonadenomas (P < .001). Delayed enhanced CT at 10 minutes (sensitivity, 92%; specificity, 95%) and 30 minutes (sensitivity, 97%; specificity, 100%) was more accurate for differentiation of adenomas and nonadenomas than unenhanced CT (sensitivity, 82%; specificity, 95%). CONCLUSION: Adrenal adenomas exhibit greater washout of contrast material than do adrenal nonadenomas. The percentage change in washout of contrast material is a useful adjunct to absolute CT attenuation values in differentiation of adrenal adenomas and nonadenomas.
- Find related publications in this database (using NLM MeSH Indexing)
- Adenoma - pathology
- Adolescent - pathology
- Adrenal Gland Neoplasms - pathology
- Adult - pathology
- Aged - pathology
- Aged, 80 and over - pathology
- Analysis of Variance - pathology
- Biopsy - pathology
- Carcinoma - pathology
- Child - pathology
- Contrast Media - administration and dosage
- Female - administration and dosage
- Follow-Up Studies - administration and dosage
- Forecasting - administration and dosage
- Humans - administration and dosage
- Image Enhancement - methods
- Image Processing, Computer-Assisted - methods
- Iohexol - administration and dosage
- Male - administration and dosage
- Middle Aged - administration and dosage
- Predictive Value of Tests - administration and dosage
- Sensitivity and Specificity - administration and dosage
- Time Factors - administration and dosage
- Tomography, X-Ray Computed - methods
- Find related publications in this database (Keywords)
- Adrenal Gland
- CT
- Adrenal Gland
- Neoplasms
- Computed Tomography (CT)
- Contrast Enhancement
- Computed Tomography (CT)
- Quantitative