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SHR Neuro Cancer Cardio Lipid Metab Microb
John, T; Roschinsky, T; Douschan, P.
Echocardiographic evaluation of the pulmonary circulation and right ventricular functional unit during exercise and its clinical value.
Curr Opin Pulm Med. 2025;
Doi: 10.1097/MCP.0000000000001186
PubMed
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- Leading authors Med Uni Graz
- Douschan Philipp
- John Teresa
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- Abstract:
- PURPOSE OF REVIEW: In this review, we provide an overview of the echocardiographic evaluation of the pulmonary circulation - right ventricular functional unit during exercise and its clinical value. RECENT FINDINGS: An increased understanding on the physiological response of pulmonary hemodynamics during exercise and evidence of the impact of an abnormal mean pulmonary arterial pressure (mPAP)/cardiac output (CO) slope on survival led to the reintroduction of exercise pulmonary hypertension (EPH), defined as a mPAP/CO slope >3 mmHg/l/min, in the current European Society of Cardiology/European Respiratory Society (ESC/ERS) guidelines for pulmonary hypertension. Additionally, noninvasive exercise echocardiography may enable easy and readily available assessment of pulmonary exercise hemodynamics. SUMMARY: Impaired pulmonary exercise hemodynamics are considered early hemodynamic signs of cardiopulmonary disease. In order to diagnose EPH, exercise right heart catheterization (RHC) is needed, which is invasive, highly cost- and staff intensive and reserved to expert centers. Noninvasive surrogates derived from exercise echocardiography might be an appropriate alternative to invasive RHC.