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SHR Neuro Cancer Cardio Lipid Metab Microb
Schremmer, T; Dejaco, C; Recker, F; Aschwanden, M; Boumans, D; Bruyn, GA; Chrysidis, S; Daikeler, T; Nielsen, B; De, Miguel, E; Diamantopoulos, AP; Dohn, UM; Duftner, C; Germano, G; Haagsma, C; Hartung, W; Hocevar, A; Iagnocco, A; Juche, A; Karakostas, P; Karalilova, R; Keller, KK; Sarker, B; Smith, K; Tischler, V; Macchioni, P; Milchert, M; Monti, S; Mukhtyar, C; Naredo, E; Schmidt, WA; Seitz, L; Terslev, L; Wakefield, RJ; Schäfer, VS.
OMERACT GCA phantom project: validation of a 3D-printed ultrasound training phantom for diagnosis of giant cell arteritis.
RMD Open. 2025; 11(1):
Doi: 10.1136/rmdopen-2024-005316
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- Leading authors Med Uni Graz
- Dejaco Christian
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- Abstract:
- OBJECTIVE: Ultrasonography is crucial for diagnosing giant cell arteritis (GCA); however, training opportunities are rare. This study tested the reliability of ultrasonography findings and measurements of the intima-media thickness (IMT) among ultrasonography experts by using phantoms of the axillary (AA) and temporal arteries (TA) created with high-resolution 3D printing. METHODS: Twenty-eight participants from 12 European countries received eight sets of phantoms of the AA and the superficial TA (including common, frontal and parietal branches), which were examined in a blinded fashion according to a predefined protocol and evaluated based on Outcome Measures in Rheumatology (OMERACT) GCA ultrasound definitions. Due to difficulties with the delineation of the intima-media complex, the parietal branch of the phantoms was modified, and a second round was conducted. The IMT was measured, and phantoms were classified as normal or vasculitic. RESULTS: In both rounds, the phantoms were correctly classified as normal/abnormal in >81% of cases yielding a Fleiss' kappa of 0.80 (95% CI 0.78 to 0.81) in round 1 and 0.74 (95% CI 0.72 to 0.75) in round 2. IMT measurements revealed an intraclass correlation coefficient (ICC 1.1) of 0.98 (95% CI 0.98 to 0.99) in both rounds. Intrarater reliability was good with a median Cohens Kappa of 0.83 and median ICC of 0.78. CONCLUSION: The study demonstrated high reliability among ultrasound experts in applying the OMERACT ultrasound definitions for GCA and in measuring the IMT using a 3D-printed phantom of the AA and TA. This phantom could assist clinicians in training to assess the large arteries of patients with suspected or established GCA.
- Find related publications in this database (using NLM MeSH Indexing)
- Giant Cell Arteritis - diagnosis, diagnostic imaging, pathology
- Humans - administration & dosage
- Phantoms, Imaging - administration & dosage
- Printing, Three-Dimensional - administration & dosage
- Ultrasonography - methods
- Temporal Arteries - diagnostic imaging, pathology
- Reproducibility of Results - administration & dosage
- Carotid Intima-Media Thickness - administration & dosage
- Female - administration & dosage
- Male - administration & dosage
- Axillary Artery - diagnostic imaging
- Find related publications in this database (Keywords)
- Giant Cell Arteritis
- Ultrasonography
- Vasculitis