Medizinische Universität Graz - Research portal
Selected Publication:
Zechner, PM.
Die Bedeutung von BNP und NT-proBNP in Diagnostik, Prognoseabschätzung und Therapiemonitoring kardialer Erkrankungen - Literaturrecherche mit anschließender Konklusion.
[ Diplomarbeit/Master Thesis ] Graz Medical University; 2009. pp.77.
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- Authors Med Uni Graz:
- Zechner Peter
- Advisor:
- Fruhwald Friedrich
- Altmetrics:
- Abstract:
- BNP and NT-proBNP are released from cardiac myocytes in response to volume or pressure overload. Since its first description in 1988 the importance of BNP and NT-proBNP was studied intensively. In the setting of acute dyspnea both natriuretic peptides provide higher diagnostic accuracy than clinical examination and reduce medical costs and hospital length of stay as well. If chronic heart failure is suspected, BNP and NT-proBNP provide good diagnostic accuracy for the presence of left ventricular dysfunction. However, the use of BNP or NT-proBNP as a screening tool for heart failure in the general population cannot be recommended. BNP and NT-proBNP provide important prognostic information in patients with congestive heart failure, acute coronary syndrome, valvular diseases and pulmonary embolism. In patients with congestive heart failure BNP and NT-proBNP can be used in the evaluation of treatment efficacy. Furthermore, BNP or NT-proBNP guided therapy of heart failure can reduce mortality.