Medizinische Universität Graz - Research portal

Go directly to the nagivation.
Go directly to the content.

Navigation/Search

Selected Publication:

Mittergradnegger, F.
Hyperbare Oxygenierung und Verbrennungen. Eine retrospektive Analyse.
[ Diplomarbeit/Master Thesis ] Graz Medical University; 2010. pp.155. [OPEN ACCESS]
FullText

Authors Med Uni Graz:
Advisor:: Smolle-Juettner Freyja-Maria
Altmetrics:
Abstract:: ABSTRACT The treatment of severe burns is one of the most complex fields of modern medicine. Despite the continuous progress in the development of therapy standards, treatments of large area burns still show a high number of complications resulting in an unfavourable prognosis. Hyperbaric oxygenation (HBO) therapy (pure oxygen administered under hyperbaric conditions) as an additional therapy for patients suffering from severe burns has been studied and vigorously discussed. The success of this therapy in human use is disputed, however, there are a number of animal studies that lead to unambiguos results. In the period from 1999 to 2009, 215 patients were treated for severe burns at the Universitätsklinik Graz. 86 out of these 215 patients had additional HBOT (hyperbaric oxygenation therapy), the remaining 127 patients were treated conventionally. The data of the patients have been analyzed retrospectively. Particular emphasis was set upon the difference in terms of duration of hospitalization, mortality, the number of split-skin grafting and other surgical interventions as well as the incidence of complications such as sepsis and renal failure. No significant difference in mortality or incidence of complications was found. However, a significant positive effect of HBOT could be verified concerning the number of surgical interventions and grafting and the duration of hospitalization. The application of additional HBOT in higher degree burns has a positive impact resulting in a reduction of necessary surgical treatments and a shorter duration of hospitalization in comparison to conventional treatment. On the basis of these results HBOT can be seen as an advisable recommendable additional therapy for patients suffering from severe burns.