Medizinische Universität Graz - Research portal
Selected Publication:
Prodinger, P.
Morphologic study of possible donor sites for lipoaumentation of the vocal folds
[ Dissertation ] Graz; 2004.
- Authors Med Uni Graz:
- Advisor:
- Friedrich Gerhard
- Altmetrics:
- Abstract:
- The lipoaugmentation technique reveals a possibility of treatment for patients suffering from glottic insufficiency. After a short introduction, the second part of the paper gives a brief description of the method and reviews studies and follow-ups concerning this topic. Different forms of harvesting, processing and injecting were compared and described. At last results, complications and problems are summarized. The third part is a line-up of possible donor sites for harvesting. Surgical accessibility, donor site morbidity and qualities of the fatty tissue determine regions of interest. Each of these regions is described anatomically and examined by the use of MRI pictures. Series of male and female patients were analyzed retrospectively and volumes of solid fat pads as well as diameters of subcutaneous layers were measured to predict the amount of harvestable tissue. Intersexual differences were figured out and the surgical access, respecting anatomical basics, declared. A cadaveric section was performed to describe the enoral approach to the buccal fat pad; basic knowledge concerning the metabolism and tissue structure of different donor regions is given. Results indicate, that of subcutaneous donor sites former in literature mentioned regions are showing favourable tissue characteristics. Distribution of a deep, metabolic inert and predestined for harvesting, and a superficial subcutaneous layer of the abdominal wall is possible and should be considered. Another subcutaneous source is the neck¿s layer. Of constitutional fat pads, the buccal fat pad shows potential as donor site, especially for vocal fold augmentation. The fourth part reviews and discusses methods of harvesting, processing, pharmaceutical treatment and application of autologous fat grafts in general, conclusions should gibe an idea of how to optimize the lipoaugmentation method.