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Selected Publication:

Bonelli, RM.
Pharmacotherapy in Huntington's disease
[ Dissertation ] Graz Medical University ; 2004. pp.100.

 

Authors Med Uni Graz:

Bonelli Raphael

Advisor:

Hofmann Peter

Pieringer Walter

Altmetrics:

Abstract:

Huntingtons disease is an autosomal dominant inherited, neuropsychiatric which comprises progressive motor, cognitive, and behavioural symptoms. Its core pathology involves degeneration of the basal ganglia in particular the caudate and putamen and is caused by a single autosomal gene coding for a mutant form of the protein huntigton. At the present time the only treatment available in Huntingtons disease are symptomatic ones. There are several substances available today for the treatment of chorea. Other neurological symptoms, on the other side, are often amenable to treatment, and relief of these symptoms may provide significant improvement in quality of life. Finally, some potential neuroprotective agents are presented.

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