Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Milcher, M.
Regional histological and microstructural variation within the uterosacral ligament in context of pelvic floor disfunction
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp.
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- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Hammer Niels
- vom Scheidt Annika
- Altmetrics:
- Abstract:
- Objective: The uterosacral ligaments (USL) are important anatomical structures in the female pelvis. They extend from the caudal part of the uterus and the cervix, running laterally around the rectum, and fan out to connect with the endopelvic fascia at the sacrum and the fascia of the pelvic floor muscles. It is hypothesized that the microstructure and mechanical properties of the USL change with age and in cases of pelvic floor dysfunction due to tensile forces. This may contribute to the development of pelvic organ prolapse (POP). The aim of this study was to analyze histological and microstructural differences in various regions of the USL. Additionally, we aimed to investigate whether the "deep layer" mentioned in some studies - a deeply running part of the USL extending toward the pelvic floor muscles - can be identified macroscopically and histologically.