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Elmer, P.
Value of prognostic scoring models in patients with spinal and extremity bone metastases.
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2024. pp.

Authors Med Uni Graz:
Advisor:: Leitner Lukas; Smolle Maria Anna
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Abstract:: Background: Cancer treatment has rapidly advanced over the past few decades, improving prognosis and life expectancy. Consequently, the number of patients developing bone metastases has increased, with a subsequent need for adequate therapy goals and treatment. In the decision-making progress regarding best treatment for patients with metastatic bone disease, their prognosis plays an integral role. As prognosis depends on various factors, prognostic scoring models have been developed in patients with spine and extremity metastases. To implement such a score in everyday clinical practice, it should be repeatedly validated, easy to use, and reliably and accurately estimate the patient's prognosis. In this study, we set out to assess nine different prognostic scoring models regarding their prognostic accuracy. We investigated whether the differentiation between spinal and extremity metastases commonly employed in the scores investigated is adequate, or whether a uniform applicability of the scores regardless of the development cohort is possible.