Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Hinterhoelzl, F.
The Impact of Portosystemic Shunts on Bile Acid Metabolism in Patients with Liver Cirrhosis - A Pilot Study
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp.
- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Zollner Gernot
- Altmetrics:
- Abstract:
- Background: While elevated bile acid concentrations in serum are considered a key characteristic of cholestatic liver diseases, changes in bile acid concentrations and profiles in liver cirrhosis without underlying cholestasis have received less attention. Since such changes can be both a consequence and a potential driver of advanced liver diseases and their complications, this study aims at characterizing the deviations in the bile acid profile in patients with liver cirrhosis more precisely. Additionally, we attempt to explore fluctuations in the bile acid profile, following the placement of a transjugular portosystemic shunt (TIPS).