Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Suljevic, O.
CHARACTERIZING BONE-IMPLANT-INTERFACE OF MG-BASED IMPLANTS UNDER THE INFLUENCE OF PHYSICAL EXERCISE
PhD-Studium (Doctor of Philosophy); Humanmedizin; [ Dissertation ] Mediziniche Universität Graz; 2025. pp.
- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Sommer Nicole
- Weinberg Annelie-Martina
- Altmetrics:
- Abstract:
- Biodegradable implants, such as magnesium (Mg)-based implants, have been subjected to intensive research in the last two decades due to their potential of replacing long-existing permanent implants in the field of orthopedics and traumatology. The main favorable characteristics of Mg-based implants are biodegradation, biocompatibility and mechanical characteristics similar to those of a human bone. In regard to patient safety, new materials need to be vigorously tested under different circumstances. Several studies demonstrated a positive postoperative influence of physical exercise on the musculoskeletal system. However, it still remains elusive, whether immediate load-bearing or even exercise in the early stage after implantation supports bone formation or might induce adverse reactions. Hence, we hypothesized that early postoperative exercise promotes bone healing in rats, and affects bone-implant-interface after Mg implantation.