Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Gendy, K.
Peak Width of Skeletonized Mean Diffusivity (PSMD) and cognition in healthy adults
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp. 62
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- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Enzinger Christian
- Seiler Stephan
- Altmetrics:
- Abstract:
- Objective: The "Peak Width of Skeletonized Mean Diffusivity" (PSMD) has been shown to be a promising DTI marker to assess white matter integrity, which is highly associated with cognitive health. There are few papers that have investigated associations between PSMD and cognition, in particular only two longitudinal studies. The first aim of this work was to investigate associations between PSMD and cognition in cognitively healthy adults in a cross-sectional study. The main aim of the work was to longitudinally investigate whether PSMD changes are related to cognitive changes over time. In addition, associations between PSMD, age, gender, vascular risk factors, white matter hyperintensities, and brain volume were investigated.