Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Wagner, L.
Evaluation of palliative third line treatment in patients with metastatic colorectal cancer
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2024. pp. 81
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- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Gerger Armin
- Riedl Jakob
- Altmetrics:
- Abstract:
- Despite the development of new targeted therapy options for metastatic colorectal cancer (mCRC), the prognosis in advanced disease remains poor. Until recently, only two monotherapies, Regorafenib and TAS-102, were available for palliative third-line treatment. The recently published randomised phase 3 “SUNLIGHT” trial showed that the combination of TAS-102+Bevacizumab (TAS-102+Bev) was superior to TAS-102 monotherapy. However, there is very limited data on the efficacy of this treatment strategy outside of a clinical trial setting.