Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Foelser, L.
The role of the Subthalamic Nucleus in facial expression in Parkinson’s disease
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2024. pp. 77
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- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Hirschbichler Stephanie
- Schwingenschuh Petra
- Altmetrics:
- Abstract:
- The objective of this work was to firstly, summarize the present body of knowledge on hypomimia in Parkinson's disease (PD) with a narrative review of the currently available literature. Secondly, it was to investigate the effects of deep brain stimulation (DBS) within the subthalamic nucleus with and without the concurrent administration of oral dopaminergic therapy on hypomimia, measured by the MDS-UPDRS-III subitem 19. A secondary aim is to study these effects on motor (MDS-UPDRS-III total, axial, and appendicular score) and non-motor symptoms (depression, anxiety, and apathy) of Parkinson’s disease and to find possible correlations. This should help further categorize hypomimia in PD patients as a motor or a non-motor symptom.