Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Schretthauser, F.
PROPORTION OF FRACTURES IN TUMOUR PATIENTS WITHOUT HISTOLOGICAL EVIDENCE OF MALIGNANT TISSUE IN THE FRACTURE AREA
A retrospective, descriptive study of atypical and pathological fractures of the humerus and femur
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2024. pp. 71
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- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Reinbacher Patrick
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- Abstract:
- In tumour patients, healthy bone metabolism can be disrupted by various factors. Primary and secondary bone tumours, life prolonging therapies or general comorbidities should be mentioned here as examples. Administration of bone modifying agents (BMA) for treatment of skeletal related events (SRE) in bone metastases is shown to be a risk factor for atypical femoral fractures (AFF). Since life expectancy in tumour patients is increasing and dosages of bisphosphonates (BP) and denosumab in tumour patients is relatively high, an increase of AFF is feared. The aim of the thesis is to determine the proportion of non-tumorous humeral and femoral fractures, to estimate the proportion of AFF and atypical humeral fractures (AHF).