Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Eimer, M.
Contraceptives for men
A feasible alternative or still an illusion?
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2023. pp. 92
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- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Lippe Irmgard Theresia
- Schicho Rudolf
- Altmetrics:
- Abstract:
- Background: The 121 million unintended pregnancies that occur each year pose major health and socio-economic risks. In addition, uncontrolled population growth is a major burden on the planet. The aim of this paper is to provide a structured and up-to-date overview of male contraception. This work provides an easy-to-understand theoretical part about the male reproductive system, which serves as a basis for understanding the mechanisms of action and side effects of the different substances. Methods: The method chosen for this thesis was a literature review. Relevant medical literature was searched using PubMed and Google Scholar. The Male Contraceptive Initiative website, Calliope The Contraceptive Pipeline Database and the Center for Male Contraceptive Research and Development were used as sources of recent relevant research on the main compounds. Results: This paper presents the most recently published scientific evidence on four hormonal and 32 non-hormonal male contraceptives, as well as the latest figures on their acceptability in society. New technologies have enabled researchers to identify many more targets for potential contraceptives. This paper is limited to information on the most important compounds and targets in active development. Conclusion and Discussion: Despite promising research, there are several challenges to the development and uptake of male contraceptives. Social and cultural norms around gender roles and contraception are a major challenge. There are also concerns about potential side effects, such as reduced libido, mood changes and fertility problems, which may need to be addressed in future research. In conclusion, male contraceptives have the potential to offer individuals and couples more options for preventing unwanted pregnancy. While there are some challenges to their development and uptake, ongoing research and development is promising for the future of male contraception.