Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Mogl, A.
FAT GRAFTING IN PLASTIC SURGERY
a systematic literature review of its state-of-the-art applications
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2023. pp. 86
[OPEN ACCESS]
FullText
- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Spendel Stephan
- Tuca Alexandru
- Altmetrics:
- Abstract:
- Background: Fat grafting is a surgical treatment that involves harvesting adipose tissue from one region of the body and then reintroducing it as a free graft to another region of the body. Autologous fat possesses a number of characteristics that make it an effective filler. Since the adipose tissue is acquired from the patient's own body, there is no risk of anaphylactic reaction or rejection, and sufficient quantities are readily accessible in the majority of patients. Because of these properties, it is currently commonly employed in plastic surgery for a wide range of reconstructive and cosmetic purposes. Aim: Because techniques in clinical medicine and medical research are continually developing, the aim of this thesis is to give an up-to-date and comprehensive overview of fat grafting applications in plastic surgery. Methods: A systematic literature search was conducted on the National Library of Medicine's MEDLINE database using PubMed as a search engine with the search terms: "plastic surgery" AND ("autologous fat transplantation" OR "fat grafting" OR lipofilling OR lipomodelling OR "fat transplantation" OR "adipose tissue transplantation"). Furthermore, the search was limited to "English" publications released after 2010. The search results were manually screened for articles concentrating on applications of fat grafting in plastic surgery based on title or abstract. Finally, the most suitable articles for each application, chosen based on their abstracts, were retrieved, and reviewed in their entirety before being cataloged based on their respective applications. Results: Using the specified systematic search strategy, 28 articles were retrieved from the 1,649 publications returned by the initial search criteria. From those publications, 21 distinct applications were extracted, each of which was then thoroughly detailed. Discussion: The systematic search yielded a number of different applications for autologous fat grafting that were not addressed in previous overviews of fat grafting applications. Some of the applications, however, are based on only a few procedures, and further research and controlled studies are required to establish them in the field of plastic surgery. Although fat grafting generated excellent results in the majority of instances, some issues, such as complications, oncological safety, and varying retention rates, need to be kept in mind. Conclusion: A more thorough review of fat grafting applications in plastic surgery than previously available was developed using a systematic literature search strategy.