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Honnef, G.
Evaluation of the usefulness of Non-invasive Serum Haemoglobin Measurement in a Perioperative Setting: Prospective Observational Study
Doktoratsstudium der Medizinischen Wissenschaft; Humanmedizin; [ Dissertation ] Medizinische Universität Graz; 2023. pp. 91 [OPEN ACCESS]
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Authors Med Uni Graz:
Advisor:: Bornemann-Cimenti Helmar; Sandner-Kiesling Andreas
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Abstract:: Introduction: The objective of this dissertation was to provide a comprehensive analysis of the potential benefits of non-invasive haemoglobin (Hb)measurement devices in identifying preoperative anemia.This change of routine care could help minimizing instances where anemic patients are overlooked in the run-up to surgery, aligning with the principles of a PatientBlood Management(PBM) approach. Materials and Methods: Prospective observational studyconducted in a preoperative clinic, involving adult patients undergoing anesthetic evaluation. Alongside laboratory Hb measurements, these patients also underwent non-invasive measurements. Results–Findings: 1216 patients were included during their preoperative evaluation. 109 (9.3%) of these patients were found to be anemic by invasive laboratory Hb measurement. The sensitivity of the non-invasive Hb (SpHb) measurement device to detect the anemic patients was 0.50 (95% CI 0.37 to 0.63) in women and 0.30 (95% CI 0.18 to 0.43) in men.Specificity was 0.97 (95% CI 0.95 to 0.98) in men and 0.93 (95% CI 0.84 to 1.0) in women. This results in a rate ofcorrectly classified patientsof84.7% for men and 89.4% for women. Positive predictive value for SpHb was 0.50 (95% CI: 0.35 to 0.65) in men and 0.40 (95% CI 0.31 to 0.50) in women; negative predictive value was 0.93 (95% CI 0.92 to 0.94) in men and 0.95 (95% CI 0.94 to 0.96) in women. Discussion: Because of its low sensitivity albeit high specificity, SpHb measurement is poorly suitable for the detection of preoperative anemia in both, male and female patients under real-world conditions.