Medizinische Universität Graz - Research portal
Selected Publication:
Stelzer, I.
Effects of lifestyle factors on Inflammatory Bowel Disease and possible implications for clinical treatment - a Scoping Review
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2023. pp. 91
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- Authors Med Uni Graz:
- Advisor:
- Holasek Sandra Johanna
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- Abstract:
- Introduction: Severe side effects of a lifelong immune modulating therapy can negatively affect outcome and quality of life for patients with Inflammatory Bowel Disease (IBD). Scientific results show that a deeper consideration of lifestyle factors does not only play a role in the development and progression of IBD, but also represents an important part in medical IBD therapy. Aim: To bring together the current state of scientific knowledge about the relevance of lifestyle factors in medical treatment of IBD that meets the requirements and principles of a bio-psycho-social therapy. Method: Based on the guidelines of a 'Preferred Reporting Items for Systemic Reviews and Meta-Analyses extension for Scoping Reviews' (PRISMA-ScR), a scoping review about the impact of lifestyle factors on IBD was conducted with initial detection of high-ranking scientific publications and was subsequently summarized in tabular form. Besides, a final evaluation on the therapeutic significance of the categories 'Nutrition', 'Mental Health' and 'Physical Activity' was performed. Results: The course of the literature selection was presented graphically in PRISMA flow diagram, after predefinition of exclusion criteria (impact factor, language, actuality): starting with results of the PubMed search (n = 1052), and via the selection process for full-text screening (n = 129), to the final choice of relevant publications (n = 40). The most important key statements of selected review papers were summarized, and main results of the scoping review were provided in tabular form. Beside the comparison of protective and harmful lifestyle factors, the advantages and disadvantages of the most common nutritional interventions were listed. In addition, the most frequently recommended psychological interventions for the treatment of IBD patients with psychological disorders were summarized. Finally, positive, and negative effects of physical activity on the well-being of IBD patients were compared with each other. Discussion: The inclusion of different lifestyle factors in the medical treatment of IBD, which corresponds with the principle of a bio-psycho-social therapy, is becoming increasingly important. The structured presentation of evidence-based, nutritional, and psychological interventions as well as physical activity offers a possible decision-supporting tool in the sense of an individual, personalized medical treatment of IBD patients.