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Hoebarth, AM.
Clinical Outcome of Patients with Infantile Hemangioma of the Scalp before, during and after the Implementation of oral Propranolol Therapy - a Retrospective Analysis
[ Diplomarbeit/Master Thesis (UNI) ] Karl Landsteiner Privatuniversität für Gesundheitswissenschaften; 2021. pp.99.

Authors Med Uni Graz:
Advisor:: Gasparella Paolo; Haxhija Emir
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Abstract:: Introduction: Infantile Hemangiomas (IH) are the most common benign tumors of infancy affecting up to 10% of all infants. Most lesions follow an uncomplicated clinical course, but in about 12% of cases, complications are observed in particular, scalp IH have been reported to cause alopecia. The treatment of IH was revolutionized in 2009 by the evidence of the efficacy of oral propranolol. This study aims to investigate the change in treatment modality of scalp IH over the past 20 years and to evaluate the clinical outcome in terms of alopecia and scaring. Methods: We retrospectively reviewed the clinical charts of 105 patients with scalp IH treated from 2000 to 2020 at the Department of Pediatric and Adolescent Surgery at the University Hospital of Graz. The cohort was split into three subgroups depending on the period of treatment in relation to the implementation of oral propranolol for treatment of IH in 2009: Group 1 (2000-2009), Group 2 (2010-2014) and Group 3 (2015-2020). (...)