Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Direkt zur Navigaton springen.
Direkt zum Inhalt springen.

Navigation/Suche

Gewählte Publikation:

Gran, J.
Choroidal Volume Measurements with Optical Coherence Tomography Before and After External Counterpulsation
Humanmedizin; [ Diplomarbeit ] Medical University of Graz; 2021. pp.

Autor*innen der Med Uni Graz:
Betreuer*innen:: Seidel Gerald; Woltsche Nora
Altmetrics:
Abstract:: External counterpulsation is a noninvasive therapy for coronary artery disease shown to improve peripheral flow-mediated dilation. The purpose of this thesis is to examine potential changes in choroidal volume following external counterpulsation. Three groups of study participants (healthy, smokers and diabetics) were examined with Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography before and after a 45-minute session of External Counterpulsation. These investigations were part of a larger study focusing on retinal vessel analysis after personalized shear rate therapy (RAST). Choroidal volume across all groups increased significantly at an average of 2,59% ± 2,77% (range -3,09% to 10,19%, p < 0,001). The healthy subgroup showed a significant average augmentation of 3,22% ± 2,46% (range 0,26% to 7,67%; p < 0,001). The diabetics showed an average augmentation of 2,70% ± 2,93% (range 0,28% to 10,19%, p = 0,012), while smoking study participants showed an average increase in choroidal volume of 1,76% ± 2,98% (range -3,09% to 6,16%, p = 0,055). Subfoveal choroidal thickness increased significantly at an average of 4,26% ± 6,36% (range -9,69% to 18,21%, p < 0,001) across all groups. Subfoveal choroidal thickness increased at an average of 4,41% ± 6,58% (range -9,69% to 14,29%, p 0,009) in the healthy subgroup, 4,8% ± 6,17% (range -2,39% to 18,21%, p 0,0055) in the smoking group and 3,15% ± 6,73% (range -7,31% to 14,66%, p 0,152) in the diabetic group. The results of this study suggest that external counterpulsation may in the short term increase choroidal volume in non-smoking, otherwise healthy individuals and early diabetics.