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Gewählte Publikation:

Jakic, M.
Immunomodulatory effects of photo(chemo)therapy in cutaneous T-cell lymphoma.
[ Diplomarbeit/Master Thesis (UNI) ] University of Graz; 2019. pp.66.
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Autor*innen der Med Uni Graz:

Betreuer*innen:

Vieyra Garcia Pablo Augusto

Wolf Peter

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Abstract:

In Cutaneous T-cell lymphoma (CTCL), neoplastic T-cells feed from chronic inflammation. These cells are infiltrated in the skin generating lesions of progressive severity. Lesional skin is also populated by non-malignant T-cells and other immune cells that may play an important role in the development of this disease. This is suggested by the fact that a treatment regime like psolaren + UVA (PUVA) in parallel to induce clinical improvement also trigger immune tolerance and apoptosis. Nevertheless, the role of the immunomodulatory effects of photo(chemo)therapy remains elusive(...)

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