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Gewählte Publikation:

Eidherr, M.
Etiology and timing of vitrectomy in eyes with non-diabetic vitreous hemorrhage
Humanmedizin; [ Diplomarbeit ] Graz Medical University; 2019. pp. 60 [OPEN ACCESS]
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Autor*innen der Med Uni Graz:
Betreuer*innen:
Falb Thomas
Ivastinovic Domagoj
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Abstract:
1. OBJECTIVE: The causes of vitreous hemorrhage, including the timing of surgical intervention and the development of visual acuity in eyes of non-diabetic patients who underwent first-time vitrectomy were studied. 2. STUDY DESIGN: Retrospective comparative case series. 3. METHODS: All eyes of non-diabetic patients that underwent first-time vitrectomy with the main diagnosis “vitreous hemorrhage” in the period from 2000 to 2015 were evaluated. Exclusion criteria were a previous vitrectomy on the affected eye or the diagnosis of diabetes mellitus. Main outcome measures were the etiology of vitreous hemorrhage, the timing of surgical intervention and the development of visual acuity. Depending on the time interval between initial presentation and vitrectomy patients were split into an early vitrectomy group (<30 days) and a delayed vitrectomy group (>30 days). Subsequently, differences in the etiology and the visual development between both groups were analyzed. 4. RESULTS: 161 eyes of 158 patients were included in this study. Most common cause for vitreous hemorrhage was retinal vein occlusion with 27.3%. Retinal tears with retinal detachments more often caused vitreous hemorrhage in our study than retinal tears without retinal detachment (11.8% and 7.5%, respectively). Vitreous detachment without retinal tear was causative for vitreous hemorrhage in 8.7%. Mean time between initial presentation and vitrectomy was 65.1 ± 65.7 days. Early vitrectomy was performed in 46.2% of the eyes and significantly more often in eyes with retinal detachment, trauma or an operative complication underlying vitreous hemorrhage. Mean time to surgery in this group was 12.8 ± 9.2 days, compared to 93.3 ± 70.6 days in the delayed vitrectomy group. Vitrectomy improved vision significantly in both groups and no difference in the final visual acuity was found between the two of them. 5. CONCLUSION: Various diseases can cause vitrectomy requiring vitreous hemorrhage in non-diabetic patients. Retinal vein occlusion, posterior vitreous detachment and retinal tears with or without retinal detachment were identified as the most common indications for vitrectomy. Vitrectomy improves vision significantly, independent of when surgery is performed.

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