Medizinische Universität Graz - Research portal
Selected Publication:
Palfinger, C.
Thermal and Non-thermal Tumour Ablation Techniques in Interventional Radiology
Humanmedizin; [ Diplomarbeit ] Graz Medical University; 2016. pp.
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- Authors Med Uni Graz:
- Advisor:
- Fuchsjäger Michael
- Wimmer Thomas
- Altmetrics:
- Abstract:
- Abstract In the last decades percutaneous, image-guided tumor ablation techniques using both thermal and non-thermal energy sources have become well established for the treatment of focal malignancies. The purpose of this thesis is to describe and to compare different thermal and non-thermal ablation techniques, which are currently used for percutaneous image-guided tumor ablations in interventional radiology and oncology procedures, such as radiofrequency ablation, cryoablation, microwave ablation, high intensity focused ultrasound and irreversible electroporation. Image-guided percutaneous treatment is gaining importance as minimally invasive therapeutic option in patients not suitable for surgical treatment, as salvage therapy and even as primary therapy for small tumors. Beside established ablation techniques, novel methods are emerging as new players in this field. Therefore, it is of particular importance to define the capabilities, advantages and disadvantages of each method in respect to various kinds of disease and patient outcome. This thesis will deliver a side-by-side review of these techniques based on current literature including both basic translational science as well as clinical studies. Each technique will be covered from technical background, to current clinical applications and outcomes as well as future outlooks. Apart from one part of this work, which will cover female breast tumor ablation and thus is specifically important for female patients, tumor ablation techniques are equally beneficial for both, male and female patients.